Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation
نویسندگان
چکیده
منابع مشابه
Woodchuck Hepatitis Virus Post-Transcriptional Regulation Element (WPRE) Promotes Anti-CD19 BiTE Expression in Expi293 Cells
Background: Bispecific antibodies represent an important class of mAbs, with great therapeutic potentials due to their ability to target simultaneously two distinct epitopes. The generation of functional bispecific antibodies with the highest possible yields is particularly critical for the production of these compounds on industrial scales. Anti- CD3 × CD19 bsAb is a bispecific T-cell engager ...
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ژورنال
عنوان ژورنال: Biotechnology Advances
سال: 2018
ISSN: 0734-9750
DOI: 10.1016/j.biotechadv.2017.11.008